2022_Stevanato_Contract_Manufacturing_Skyscraper

advanced search
2023 June Paragon Medical Leaderboard

RESPIRATORY

EXPERT VIEW
THE POTENTIAL OF CONNECTIVITY AND MONITORING IN MESH NEBULISERS
Carolina Dantas and Ulf Krueger review the current connectivity and remote monitoring capabilities in mesh nebulisers – and their potential to impact patients’ healthcare journeys and the clinical development of inhaled therapies.
PULMONARY
THE APPLICATION DIVERSITY OF METERED PUMP-BASED SOFT MIST DEVICES
Marie-Christine Klein, Andreas Bilstein and Caroline Hoffmann discuss the underlying techniques involved in the use of metered pump-based soft mist devices and their application diversity.
INJECTING INNOVATIVE SOLUTIONS INTO CONNECTED DELIVERY DEVICES
EXPERT VIEW
Roger Bohannan
INJECTING INNOVATIVE SOLUTIONS INTO CONNECTED DELIVERY DEVICES
Roger Bohannan discusses the capabilities and design challenges of connected drug delivery devices.
WHEN SECONDARY PACKAGING IS A PRIMARY CONCERN
INDUSTRIALISATION
Mark Foster
Oliver Design
WHEN SECONDARY PACKAGING IS A PRIMARY CONCERN
Mark Foster discusses the challenges to optimising primary and secondary packaging for parenteral drug delivery devices, including higher level challenges from the patient perspective, as well as how these challenges present opportunities for device developers to stand out in the market.
Interview with Julien Martins & David Philbrick
INTERVIEW
Julien Martins
Paragon Medical
Interview with Julien Martins & David Philbrick
Julien Martins and David Philbrick talk exclusively with ONdrugDelivery's Guy Furness. They discuss a wide range of topics, including the services Paragon Medical provides the drug delivery industry, its wider business operations, the company’s expanded facilities in the US and Europe, and its new Advanced Surgical Innovation Center.
DESIGNING SUSTAINABILITY INTO PHARMACEUTICAL DEVICES
EXPERT VIEW
Will Davies
DESIGNING SUSTAINABILITY INTO PHARMACEUTICAL DEVICES
Will Davies discusses in detail how to address the challenges of designing sustainability into pharmaceutical devices.
SUSTAINABILITY IN DRUG DELIVERY: HOW DO WE GET THERE?
EXPERT VIEW
Tim Wooller
SUSTAINABILITY IN DRUG DELIVERY: HOW DO WE GET THERE?
Tim Wooller discusses the urgent need to transition away from disposable models of drug delivery device design and move towards reusables, providing insights into the reasons why and the methods by which this can be achieved.
ACCELERATING THE GO-TO-MARKET OF NASAL COMBINATION PRODUCTS WITH INTEGRATED SOLUTIONS
NASAL
Séverine Duband
Nemera
ACCELERATING THE GO-TO-MARKET OF NASAL COMBINATION PRODUCTS WITH INTEGRATED SOLUTIONS
Séverine Duband and Audrey Chandra discuss emerging trends in the ear, nose and throat market and how Nemera can assist in bringing new devices to market.
NAVIGATING pMDI REFORMULATION 2.0
SUSTAINABILITY
Chris Baron
Aptar Pharma
NAVIGATING pMDI REFORMULATION 2.0
Chris Baron and William Ganley examine possible responses to the environmental impact of pressurised metered dose inhalers use and consider alternative inhaler types, with a focus on the strategies and support that can accelerate the development of the next generation of pMDIs.
NAVIGATING THE CHALLENGES OF BRINGING INTRANASAL DRUG FORMULATIONS & DEVICES TO PATIENTS
NASAL
Joe Neale
Recipharm
NAVIGATING THE CHALLENGES OF BRINGING INTRANASAL DRUG FORMULATIONS & DEVICES TO PATIENTS
Joe Neale and Ross Errington explore the obstacles and opportunities facing the intranasal drug delivery market and how manufacturers can overcome them by harnessing innovative platforms like Unidose® Xtra.
NOVEL INDUSTRIAL-SCALE ELECTROSTATIC CHARGE ELIMINATION METHOD FOR INHALATION PRODUCTS
PULMONARY
Dr Orest Lastow
Iconovo
NOVEL INDUSTRIAL-SCALE ELECTROSTATIC CHARGE ELIMINATION METHOD FOR INHALATION PRODUCTS
Orest Lastow describes a novel technique for removing the built-up charge from dry powder inhaler components, offering a potential solution to the issues caused by static charges in these devices, including decreased performance, altered powder properties and increased variability in delivered dose.
DEVELOPMENT APPROACH FOR A HIGH-PERFORMANCE CAPSULE-BASED DPI
PULMONARY
Dr Mirjam Kobler
H&T Presspart
DEVELOPMENT APPROACH FOR A HIGH-PERFORMANCE CAPSULE-BASED DPI
Mirjam Kobler, Ameet Sule and Sunita Sule look at the factors affecting the performance of dry powder inhalers and discuss the company’s development of high-performance prototypes.
ARE YOU STRUGGLING TO PUT DIFFICULT POWDERS INTO CAPSULES?
PULMONARY
Andy Cleall
3P Innovation
ARE YOU STRUGGLING TO PUT DIFFICULT POWDERS INTO CAPSULES?
Andy Cleall and Ben Smith discuss process optimisation and cutting-edge technology for powder filling, including how 3P’s R500 and R1000 robotic capsule fillers are pushing the boundaries of optimal filling and how its Fill2Weight technology enables increased filling accuracy and improved yields.
THE POTENTIAL AND THE CHALLENGES OF NASAL VACCINATION
NASAL
Dr Julie Suman
Aptar Pharma
THE POTENTIAL AND THE CHALLENGES OF NASAL VACCINATION
Julie Suman and Nektaria Karavas discuss the challenges and opportunities of intranasal vaccination – showcasing current understanding for both liquid and powder products. Experimental studies highlight critical issues, the performance of commercially available devices and developments in formulation practice.
CAPSULE FILLING FOR DPIs – LINKING PROCESS SCALES THROUGH ADVANCED CHARACTERISATION AND QUALITY BY DESIGN
PULMONARY
Dr Rui Churro
Hovione
CAPSULE FILLING FOR DPIs – LINKING PROCESS SCALES THROUGH ADVANCED CHARACTERISATION AND QUALITY BY DESIGN
 Rui Churro, Carolina Lopes and João Pires discuss the value of rheological characterisation of powders to expedite and de-risk the scale-up of DPI capsule-filling processes.
ISOTHERMAL DRY PARTICLE COATING – BACK TO THE FUTURE?
PULMONARY
Dr Jasdip Koner
Aston Particle Technologies
ISOTHERMAL DRY PARTICLE COATING – BACK TO THE FUTURE?
Jasdip Koner, Abdul Ershad and David Wyatt introduce Aston Particle Technologies’ novel dry powder processing technology – isothermal dry particle coating (iDPC™) – explaining how it has the capacity to enhance and broaden the scope of what dry powder formulations can achieve in respiratory medicine.
DUE DILIGENCE – THE KEY TO SUCCESS IN DRUG DELIVERY DEVICE SELECTION
EXPERT VIEW
Matt Jones
DUE DILIGENCE – THE KEY TO SUCCESS IN DRUG DELIVERY DEVICE SELECTION
Matt Jones and Rob Veasey consider the process of matching the drug with the right delivery device and look at the importance of due diligence when “licensing in” technology.
CONSIDERATIONS WHEN SWITCHING FROM CURRENT pMDI PROPELLANTS TO NEW LOWER-GWP PROPELLANTS
EXPERT VIEW
Mark Parry
CONSIDERATIONS WHEN SWITCHING FROM CURRENT pMDI PROPELLANTS TO NEW LOWER-GWP PROPELLANTS
Mark Parry discusses the considerations that need to be made when switching from current pressurised metered dose inhaler propellants to new alternatives with lower global warming potential, including formulation, regulatory and analytical standpoints.
Pharmapack Expert Panel on Patient-Centric Digital Health: Interview with Ben Cox, Team Consulting
INTERVIEW
Dr Ben Cox
Team Consulting
Pharmapack Expert Panel on Patient-Centric Digital Health: Interview with Ben Cox, Team Consulting
With Pharmapack returning to its traditional February timing in 2023, Team Consulting will be chairing a Day 1 expert panel discussion on patient-centric digital health solutions. Interviewed here, Ben Cox provides insight into trends the panel will discuss, lays out the current status of the industry with respect to digital health and considers what to look forward to at Pharmapack this year.
ADVANCEMENTS IN MONITORING ADHERENCE – A SMART MESH NEBULISER
CONNECTIVITY
Edgar Hernan Cuevas Brun
HCmed Innovations
ADVANCEMENTS IN MONITORING ADHERENCE – A SMART MESH NEBULISER
Edgar Hernan Cuevas Brun and Yuan-Ming Hsu consider patient adherence and the role HCmed Innovations’ AdheResp mesh nebuliser plays in monitoring adherence.
DIGITAL HEALTH: ADDRESSING MODERN HEALTHCARE CHALLENGES WITH SENSORS
CONNECTIVITY
Dr Haykel Ben Jamaa
Sensirion
DIGITAL HEALTH: ADDRESSING MODERN HEALTHCARE CHALLENGES WITH SENSORS
Haykel Ben Jamaa explores why modern society needs digital health and how it is organised and implemented, with a focus on sensing technologies empowering digital health technologies.
WHY ARE INHALATION DEVICES SO DIFFICULT TO DEVELOP?
PULMONARY
Dr Orest Lastow
Iconovo
WHY ARE INHALATION DEVICES SO DIFFICULT TO DEVELOP?
Orest Lastow discusses the challenges of developing inhalation products and how best to keep costs down and prevent project delays.
STEPS TO SUCCESS IN NOSE-TO-BRAIN DRUG DELIVERY
NASAL
Reenal Gandhi
Aptar Pharma
STEPS TO SUCCESS IN NOSE-TO-BRAIN DRUG DELIVERY
Reenal Gandhi and Gemma Budd consider the multiple hurdles associated with developing nasal drug delivery solutions, current understanding of the associated biology and the advantages of alternative device designs and state-of-the-art formulation practice.
CREATING A PLATFORM FOR NEBULISATION OF A WIDE RANGE OF DRUG TYPES AND FORMULATIONS
EARLY INSIGHT
Dr Elijah Nazarzadeh
Nebu~Flow
CREATING A PLATFORM FOR NEBULISATION OF A WIDE RANGE OF DRUG TYPES AND FORMULATIONS
Elijah Nazarzadeh and John Pritchard introduce Nebu~Flow – a novel class of nebuliser technology that represents a major step in the ability to deliver drugs efficiently to the lungs. overcoming the limitations of current systems and unlocking the potential of the inhalation route, including for systemic delivery.
A ROADMAP FOR DRUG-NEBULISER COMBINATION PRODUCT DEVELOPMENT
PULMONARY
Edgar Hernan Cuevas Brun
HCmed Innovations
A ROADMAP FOR DRUG-NEBULISER COMBINATION PRODUCT DEVELOPMENT
Edgar Hernan Cuevas Brun and Yuan-Ming Hsu lay out HCmed Innovations’ roadmap for the development of drug-nebuliser combination products.
AN AIRLESS SPRAY NOZZLE TO PRODUCE A FINE AND SOFT MIST
SKIN
Dr Claire Authesserre
Eveon
AN AIRLESS SPRAY NOZZLE TO PRODUCE A FINE AND SOFT MIST
Claire Authesserre and Florian Corne discuss the current challenges faced by the topical spray-based delivery of therapeutics and how EVEON’s Ad-Mist™ spray nozzle overcomes these challenges to harness the potential of this delivery route.
GETTING A GRIP ON FRICTION – A CRUCIAL CONSIDERATION FOR INHALER DESIGN
PULMONARY
Bryan Deacon
Celanese
GETTING A GRIP ON FRICTION – A CRUCIAL CONSIDERATION FOR INHALER DESIGN
Bryan Deacon discusses the importance of considering friction when developing a new inhaler design, providing an overview of some of the basic considerations friction raises, as well as highlighting how optimising friction early with the aid of a materials expert can reduce risk, lower cost and lead to a better product overall.
EXPLORING NEW IN VITRO TESTS TO DEMONSTRATE BIOEQUIVALENCE IN INHALATION PRODUCTS
PULMONARY
Lynn Jordan
Proveris Scientific
EXPLORING NEW IN VITRO TESTS TO DEMONSTRATE BIOEQUIVALENCE IN INHALATION PRODUCTS
Proveris Scientific looks at recent advances in in vitro testing in inhalation products to demonstrate bioequivalence and discusses the company’s INVIDA platform that replicates human usage of the device.
EXPANDING THE DESIGN OF CHARACTERISATION STUDIES FOR ACCURATE HANDLING-ERROR ASSESSMENT
EXPERT VIEW
Dr Yannick Baschung
EXPANDING THE DESIGN OF CHARACTERISATION STUDIES FOR ACCURATE HANDLING-ERROR ASSESSMENT
Yannick Baschung discusses the importance of a comprehensive and accurate assessment of patient handling errors when it comes to inhaled product development.
THE INFLUENCE OF UNCERTAINTY ON CHEMICAL CHARACTERISATION
EXPERT VIEW
James Silk
THE INFLUENCE OF UNCERTAINTY ON CHEMICAL CHARACTERISATION
James Silk discusses the importance of accounting for uncertainty when characterising the extractables profile of a medication, with particular reference to the ISO 10993 standard.
POWDER CHARACTERISATION FOR DPI PERFORMANCE IN CAPSULE-BASED INHALERS
PULMONARY
Dr Salvatore Pillitteri
Granutools
POWDER CHARACTERISATION FOR DPI PERFORMANCE IN CAPSULE-BASED INHALERS
Salvatore Pillitteri, Aurélien Neveu and Sarah Zellnitz-Neugebauer discuss the analysis of three powder blends of salbutamol sulphate with distinct lactose grades, using tapped density and rotating drum methods.
DELIVERING BIOLOGICS WITH SOFT MIST INHALERS – A MARKET POISED TO EXPAND
PULMONARY
Dr Philippe Rogueda
Merxin
DELIVERING BIOLOGICS WITH SOFT MIST INHALERS – A MARKET POISED TO EXPAND
Philippe Rogueda discusses the inhalable biologics market, how the introduction of soft mist inhalers represents a significant opportunity for new and old therapeutics alike, and how the market is poised for a major expansion in therapeutic application, size and value.
ENGINEERING EXPERTISE: DESIGN FOR EXCELLENCE
INDUSTRIALISATION
Drew Jelgerhuis
Scherdel Medtec North America
ENGINEERING EXPERTISE: DESIGN FOR EXCELLENCE
Drew Jelgerhuis looks at how a design-for-excellence (DFX) systematic approach can help manufacturers achieve their objectives.
HIGH-PRECISION INJECTION MOULDS FOR INHALERS: CHALLENGES AND SOLUTIONS
INDUSTRIALISATION
Rob Doorakkers
IGS GeboJagema
HIGH-PRECISION INJECTION MOULDS FOR INHALERS: CHALLENGES AND SOLUTIONS
Rob Doorakkers and Erwin van Huijksloot discuss the challenges and solutions of engineering and manufacturing high-precision injection moulds for inhalers.
CLIPhaler – INHALATION DEVICE DESIGN REDUCED TO THE MAXIMUM
EARLY INSIGHT
Dr Klaus-Dieter Beller
CLIPhaler – INHALATION DEVICE DESIGN REDUCED TO THE MAXIMUM
Klaus-Dieter Beller discusses the advantages of the inhalation route of administration, how his principle of design simplicity has informed the design of novel inhalation devices and introduces CLIPhaler, his latest and simplest device.
THE INNOVATIONS TACKLING CHALLENGES & MAXIMISING OPPORTUNITIES IN INHALATION
EXPERT VIEW
Marco Franza
THE INNOVATIONS TACKLING CHALLENGES & MAXIMISING OPPORTUNITIES IN INHALATION
Marco Franza and Nadine Khoury look at how the latest digital technologies, manufacturing techniques and packaging materials are combining to take the manufacture of inhalers to a new level.
TAKING THE STING OUT OF VACCINES
EXPERT VIEW
Dr Heather Jameson
TAKING THE STING OUT OF VACCINES
Heather Jameson, Juliette Ngan and Omar Shah discuss the potential advantages and challenges of intranasal and inhaled vaccines in the context of global respiratory pandemics.
SOLVING COMPLEX FORMULATION & DELIVERY CHALLENGES FOR INTRANASAL DRUGS
EXPERT VIEW
Dr Paul Kippax
SOLVING COMPLEX FORMULATION & DELIVERY CHALLENGES FOR INTRANASAL DRUGS
Paul Kippax discusses the analytical techniques used for in vitro characterisation of nasal sprays, and how their use can accelerate and de-risk both innovator and generic nasal drug development.
Top